Lewis Fall known as Lewis
BSc (Hons), PhD
I joined the University of Glamorgan in June 2005 as a Senior Technician. I began my PhD part time in 2007 and loved the research process and environment. Since then, my role has changed and I was promoted to a Technical Demonstrator in 2011. In 2013, following the inclusion of my research into the REF, I was placed on a partial contract and split my time between lecturing and demonstrating until I joined the School of Applied Science as a Senior Lecturer in Human Physiology, lecturing across the Biology, Human Biology and Medical Science courses.
In my time at USW (and University of Glamorgan before it) I have worked with a number of outside groups, including providing physiological testing and support to the Welsh Rugby Union First 15 during the 2005 and 2008 grand slams.
Senior Lecturer in Human Physiology.
Course Leader BSc (Hons.) Medical Sciences
Teaching contribution to:
BI2S114 Clinical Physiology (module leader)
BI2S103 Applied Physiology (module leader)
BI1S103 Anatomy and Physiology
BI2S98 Cellular Pathology and Disease Processes
BI2S120 Clinical Practice (module leader)
BI1S11 Introduction to Clinical Practice (module leader)
BI0S100 Introduction to Anatomy and Physiology
BI0S06 Foundation Biology (Module Leader)
SR3S14 Exercise Physiology III (contribution to cardiac physiology and ECG interpretation)
Selected Publications and Abstracts
Redox‐regulation of haemostasis in hypoxic exercising humans; a randomised double‐blind placebo‐controlled antioxidant study
Fall L, Brugniaux LV, Hodson D, Marley CJ, Davies B, New KJ, McEneny J, Young IS, Bailey DM
The Journal of Physiology 2018 DOI: https://doi.org/10.1113/JP276414
Amputees at high-altitude: the sticky issue of thrombophilia
Stacey BS, Fall L, Shearer D, Steggall M, Williams IW, Lewis MH, Bailey DM
High Altitude Medicine and Biology, 2018; 19(2):211-212
Post-prandial hyperlipidaemia results in systemic nitrosative stress and impaired cerebrovascular function in the aged
Marley CJ, Hodson D, Brugniaux JV, Fall L, Bailey DM.
Clinical Science, 2017; 28;131(23):2807-2812
Arterial hypoxaemia and its impact on coagulation: significance of altered redox homeostasis
Fall L, New KJ, Evans KA, Bailey DM
Journal of Clinical Pathology, 2015; 68(9):752-4
Systemic oxidative-nitrosative-inflammatory stress during acute exercise in hypoxia; implications for microvascular oxygenation and aerobic capacity.
Woodside JD, Gutowski M, Fall L, James PE, McEneny J, Young IS, Ogoh S, Bailey DM.
Journal of Experimental Physiology, 2014; 1;99(12):1648-62
Interpretive Limitations Associated With Plasma Volume Shifts in the Clinical Assessment of Hemostasis
Fall, L. & Bailey, D. M.
Psychosomatic Medicine, 2013; 75, 222-223.
Haemostatic response to hypoxaemic/exercise stress: the dilemma of plasma volume correction
Fall, L., Evans, KA., Lewis, MH., & Bailey DM.
Journal of Clinical Pathology, 2011;64: 269-271.
Altered free radical metabolism in acute mountain sickness: implications for dynamic cerebral autoregulation and blood-brain barrier function.
Bailey DM, Evans KA, James PE, McEneny J, Young IS, Fall L, et al
The Journal of Physiology. 2009;587(1):73-85
Differential Effects on Regional Pulse Wave Velocity & Augmentation Index Following Maximal Exercise in Healthy Young Men.
Karl James New, Ashley Morgan, Trevor Harris, Lewis Fall, Julien Brugniaux, and Damian M Bailey
FASEB Journal 2012; 29, 26:1138.32
Acute Hyperoxic Exercise & Redox Regulation of Blood Coagulation.
Karl James New, Lewis Fall, Catherine Templeton, Gethin Ellis, Dave Hullin, Jane McEneny, Bruce Davies, and Damian Bailey
FASEB Journal 2011;17, 25:1107.4
Haemostatic Response To Inspiratory Hypoxia And Physical Exercise; Interpretive Implications Of Plasma Volume Shifts.
Lewis Fall, Evans KA, Sinnott A, Bailey DM
Proceedings of the Physiological Society. 2009;15:C84
Acute mountain sickness does not alter the coagulation cascade differently in susceptible and non-susceptible individuals
Lewis Fall, Evans KA Ainsle PN, Martins P, Kewley E, Bailey DM
Proceedings of the Physiological Society. 2008;11:C10
British Association of Sport and Exercise Sciences
Welsh Institute of Sport, Health and Exercise Science
I was a consultant with Richard Parks’ 737 Challenge. A successful world record attempt and pioneering 7 month race to climb the highest mountain on each of the world’s continents and venture to The South and Geographical North Poles.
I have worked with Welsh Rugby Union as part of the Physiological Testing Team to the 1st 15 from 2005-2008, during which period we won 2 Grand Slams.
I’ve also worked with Simbec Medical Research as part of a collaborative study for the Ministry Of Defence.
My principal research interests focus on the blood haemostatic system and its interaction with vascular disease.
Broadly, my research interests can be categorised as follows:
- the causes and consequences of changes coagulation seen in hypoxia/hypoxaemia
- investigating the possible “up-stream” trigger of these changes
- furthering research into the interaction of oxidation/reduction state and coagulation
- furthering quality control practices involved in the sampling of blood for haemostatic testing
My current research includes studies investigating the following:
- The role of oxidative stress in the pathopysiology of haemostasis
- The influence of plasma volume correction on the interpretation of blood-borne biomarkers of haemostasis
- The effect of different blood sampling devices and protocols on the interpretation of blood-borne biomarkers of haemostasis.
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