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Qualifications

PhD in Molecular Tumour Biology (Cardiff University)
BSc (Hons) Medical Pharmacology (Cardiff University)

Publications

Mechanistic insights of Epithelial Protein Lost in Neoplasm in prostate cancer metastasis. Collins RJ, Morgan LD, Owen S, Ruge F, Jiang WG, Sanders AJ. Int J Cancer. 2018 Aug 11. doi: 10.1002/ijc.31786. [Epub ahead of print]. PMID: 30098000

Impact of pigment epithelium-derived factor on colorectal cancer in vitro and in vivo. Harries RL, Owen S, Ruge F, Morgan M, Li J, Zhang Z, Harding KG, Torkington J, Jiang WG, Cai J. Oncotarget. 2018 Apr 10;9(27):19192-19202. doi: 10.18632/oncotarget.24953. eCollection 2018 Apr 10. PMID: 29721193

Key Factors in Breast Cancer Dissemination and Establishment at the Bone: Past, Present and Future Perspectives. Owen S, Zabkiewicz C, Ye L, Sanders AJ, Gong C, Jiang WG. Adv Exp Med Biol. 2017;1026:197-216. doi: 10.1007/978-981-10-6020-5_9. Review. PMID: 29282685

Association of breast carcinoma growth with a non-canonical axis of IFNγ/IDO1/TSP1. Lopes-Bastos B, Jin L, Ruge F, Owen S, Sanders A, Cogle C, Chester J, Jiang WG, Cai J. Oncotarget. 2017 Jun 28;8(49):85024-85039. doi: 10.18632/oncotarget.18781. eCollection 2017 Oct 17. PMID: 29156701

In vitro significance of SOCS-3 and SOCS-4 and potential mechanistic links to wound healing. Feng Y, Sanders AJ, Morgan LD, Owen S, Ruge F, Harding KG, Jiang WG.
Sci Rep. 2017 Jul 27;7(1):6715. doi: 10.1038/s41598-017-06886-6.
PMID: 28751715

Expression of Osteoprotegrin Is Enhanced in Lung Cancer Tissues and Promotes Aggressive Cellular Traits in H3122 Lung Cancer Cells.
Yu Z, Sanders AJ, Owen S, Cheng S, Yang X, Jiang WG. Anticancer Res. 2017 Aug;37(8):4277-4283. PMID: 28739719

Clinical Significance of PD1 and PDL1 in Human Breast Cancer. Uhercik M, Sanders AJ, Owen S, Davies EL, Sharma AK, Jiang WG, Mokbel K. Anticancer Res. 2017 Aug;37(8):4249-4254. PMID: 28739716

Prostate Transglutaminase (TGase-4) Induces Epithelial-to-Mesenchymal Transition in Prostate Cancer Cells. Ablin RJ, Owen S, Jiang WG. Anticancer Res. 2017 Feb;37(2):481-487. PMID: 28179293

Complement inhibitor CSMD1 acts as tumor suppressor in human breast cancer. Escudero-Esparza A, Bartoschek M, Gialeli C, Okroj M, Owen S, Jirström K, Orimo A, Jiang WG, Pietras K, Blom AM.
Oncotarget. 2016 Nov 22;7(47):76920-76933. doi: 0.18632/oncotarget.12729. PMID: 27764775

The clinical significance and impact of interleukin 15 on keratinocyte cell growth and migration. Jones AM, Griffiths JL, Sanders AJ, Owen S, Ruge F, Harding KG, Jiang WG. Int J Mol Med. 2016 Sep;38(3):679-86. doi: 10.3892/ijmm.2016.2687. Epub 2016 Jul 21. PMID: 27460304

Targeting of Receptor Activator of Nuclear Kappa B (RANK) in PC-3 Cells Increases Cell Proliferation and Matrix Adhesion In Vitro.
Owen S, Sanders AJ, Mason MD, Jiang WG. Anticancer Res. 2016 Mar;36(3):1127-34. PMID: 26977008

Importance of osteoprotegrin and receptor activator of nuclear factor κB in breast cancer response to hepatocyte growth factor and the bone microenvironment in vitro. Owen S, Sanders AJ, Mason MD, Jiang WG. Int J Oncol. 2016 Mar;48(3):919-28. doi: 0.3892/ijo.2016.3339. Epub 2016 Jan 15. PMID: 26781475

The human complement inhibitor Sushi Domain-Containing Protein 4 (SUSD4) expression in tumor cells and infiltrating T cells is associated with better prognosis of breast cancer patients. Englund E, Reitsma B, King BC, Escudero-Esparza A, Owen S, Orimo A, Okroj M, Anagnostaki L, Jiang WG, Jirström K, Blom AM. BMC Cancer. 2015 Oct 19;15:737. doi: 10.1186/s12885-015-1734-7. PMID: 26480818

A role for WISP2 in colorectal cancer cell invasion and motility.
Frewer KA, Sanders AJ, Owen S, Frewer NC, Hargest R, Jiang WG.
Cancer Genomics Proteomics. 2013 Jul-Aug;10(4):187-96. PMID: 23893926

Expression profile of receptor activator of nuclear-κB (RANK), RANK ligand (RANKL) and osteoprotegerin (OPG) in breast cancer.
Owen S, Ye L, Sanders AJ, Mason MD, Jiang WG. Anticancer Res. 2013 Jan;33(1):199-206. PMID: 23267146

Memberships

American Association for Cancer Research
British Assoociation for Cancer Research
British Pharmacological Society
European Association for Cancer Research

Areas of Expertise

Cell biology, Molecular biology, Pharamacology

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